Buffy the Vampire Slayer: S2E3

From the very beginning, Spike sets himself apart from the other vamps in town.

1) He arrives via car, destroying the "Welcome to Sunnydale" Sign. - how have the other vampires in Sunnydale arrived there?  Honestly, we don't know.  They either already exist in the town or they are created there.  So it's probably unfair of me to say that Spike arrived in a different manor not really knowing how the other vamps travel.  But to this point, we have not seen a vampire make use of this modern technology.

2) He has an actual romantic relationship with Drusilla. - We haven't seen this type of relationship between vampires yet.  Angel is able to care for Buffy, but then he has a soul so there are special rules for him.  But Spike's relationship with Drusilla goes beyond the basic Sire/Child or the Master/Servant relationships we've seen thus far from the Sunnydale Vampires.  We see that Spike actually cares for Drusilla (brought her to a place of safety, encourages her to eat and get healthy).  When they are together the entire world can disappear around them.

3) He has no respect for the rituals and doesn't listen to authority. - while the other vampires are cowering around "the Annointed One" and doing his bidding, Spike has no respect for the kid.  In the end, he even strings the Annointed One up in the sunlight and kills him.  It really seems so simple when he does it you wonder why any of the other vampires hadn't thought of it first.